Fig. 4. Epinephrine upregulates α1-AR expression in T cells of mice with CIA. The activated T cells were incubated with epinephrine for 24 h. Protein expression of α1-AR in T cells was tested by Western blot analysis. E=epinephrine; ^**p<0.01, versus intact control; ⁺p<0.05, ⁺⁺p<0.01, versus CIA group; ^#p<0.05, versus CIA + E (10^-6 M) group.